Located close to Port Colborne are several renown post-secondary institutions. Brock University and Niagara College are both located 20 minutes from Port Colborne, while McMaster University and Mohawk College are in nearby Hamilton, Ontario. 

Port Colborne is home to 8 primary schools and 2 secondary schools, with education available in both English and French. Serving Port Colborne are the District School Board of Niagara, the Niagara Catholic School Board, the Conseil scolaire Viamonde, and the Conseil scolaire de district catholique Centre-Sud. Post-secondary education is available in Niagara at several different institutions.